Tylenol Sinus Extra Strength Day + Night – Combo Pack (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine)

Tylenol Sinus Extra Strength Day + Night (Combo Pack) (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine)

Tylenol Sinus Extra Strength Day + Night Combo Pack provides fast relief from sinus pain, pressure, congestion, and headaches, helping you stay active during the day and rest comfortably at night. The Daytime Caplets offer non-drowsy relief for nasal congestion and sinus pain, while the Nighttime Caplets ease a runny nose, sneezing, and pressure to promote better sleep. With acetaminophen, phenylephrine, and chlorpheniramine maleate, this convenient combo targets multiple sinus and cold symptoms for 24-hour comfort.

Why Choose Tylenol Sinus Extra Strength Day + Night (Combo Pack) (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine)?

• Relieves sinus pain and pressure effectively.
• Reduces fever and headache caused by colds or sinus infections.
• Clears nasal congestion for easier breathing.
• Daytime formula provides non-drowsy relief to keep you active.
• Nighttime formula helps ease symptoms and promote restful sleep.
• Convenient day + night pack for 24-hour symptom management.

How to Use Tylenol Sinus Extra Strength Day + Night (Combo Pack) (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine)?

• Read the label carefully before use and follow all directions.
• Take only the recommended dosage listed on the package.
• Use Daytime caplets in the morning and afternoon as needed.
• Use Nighttime caplets before bedtime to relieve symptoms and support sleep.
• Do not exceed 8 caplets in 24 hours.
• Avoid alcohol and other products containing acetaminophen while using this medication.
• If symptoms persist for more than 7 days, consult your healthcare provider.

Important Safety Information about Tylenol Sinus Extra Strength Day + Night

• Do not use if you are allergic to acetaminophen, chlorpheniramine, or phenylephrine.
• Consult your doctor before use if you have high blood pressure, heart disease, liver disease, thyroid problems, diabetes, or glaucoma.
• Avoid driving or operating machinery after taking the nighttime dose due to possible drowsiness.
• Do not combine with other cold, allergy, or pain medications unless directed by a physician.
• Keep out of reach of children.
• In case of overdose, seek medical attention immediately, even if symptoms are not apparent.

Fact Table

 

Facts	Details
Brand Name	Tylenol Sinus Extra Strength Day + Night Combo Pack
Active Ingredients (Daytime)	– Acetaminophen 500 mg (Pain reliever/fever reducer) – Phenylephrine HCl 5 mg (Nasal decongestant)
Active Ingredients (Nighttime)	– Acetaminophen 500 mg (Pain reliever/fever reducer) – Phenylephrine HCl 5 mg (Nasal decongestant) – Chlorpheniramine Maleate 2 mg (Antihistamine)
Purpose	Temporarily relieves symptoms associated with sinus pain, nasal congestion, headache, fever, and related cold or allergy discomforts.
Dosage Form	Caplets (solid oral tablets)
Intended Use	For adults and children 12 years and older. Not intended for children under 12.
Recommended Dosage	– Daytime: 2 caplets every 4–6 hours as needed. – Nighttime: 2 caplets at bedtime as needed. – Do not exceed 8 caplets in 24 hours.
Mechanism of Action	– Acetaminophen reduces fever and pain by blocking pain signals and lowering body temperature. – Phenylephrine constricts blood vessels in nasal passages to relieve congestion. – Chlorpheniramine Maleate blocks histamine receptors to reduce sneezing, runny nose, and watery eyes.
Onset of Action	Typically within 30–60 minutes after ingestion.
Duration of Relief	Up to 4–6 hours per dose.
Key Benefits	– Relieves sinus pain and pressure. – Reduces headaches and fever. – Clears nasal congestion. – Daytime formula is non-drowsy. – Nighttime formula helps ease symptoms and improve sleep quality.
Common Side Effects	Drowsiness (nighttime), dry mouth, mild dizziness, upset stomach, nausea, or trouble sleeping (daytime).
Contraindications	– Severe liver disease. – Use with other acetaminophen-containing products. – Use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping them.
Precautions	– Consult a doctor if you have liver disease, high blood pressure, heart disease, diabetes, thyroid disorders, glaucoma, or difficulty urinating due to prostate enlargement. – Avoid alcohol consumption. – Avoid driving or operating machinery after taking nighttime formula.
Storage	Store at 20–25°C (68–77°F). Keep tightly closed and away from moisture and children.
Availability	Over-the-counter (OTC)

Common Side Effects

Like all medications, Tylenol Sinus Extra Strength Day + Night (Combo Pack) (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Drowsiness (mainly with the nighttime formula)
• Dry mouth or throat
• Mild dizziness or light-headedness
• Upset stomach or nausea

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Tylenol Sinus Extra Strength Day + Night (Combo Pack) (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine)?

You can order Tylenol Sinus Extra Strength Day + Night (Combo Pack) (Acetaminophen/ Chlorpheniramine Maleate/ Phenylephrine) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.